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Research Article
BioDiscovery 20: e11211
https://doi.org/10.3897/biodiscovery.20.e11211 (08 Feb 2017)
https://doi.org/10.3897/biodiscovery.20.e11211 (08 Feb 2017)
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Article metadata
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Introduction
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Results
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Isolation and characterization of cells expressing ABCB1 and ABCG2
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The effect of ABCB1 and ABCG2 expression on intracellular levels of dasatinib
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The effect of dasatinib on cell viability and apoptosis induction in cells expressing ABCB1 or ABCG2
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Discussion
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Materials and methods
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Chemicals
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Cell Culture
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ABCB1 and ABCG2 expression analysis using flow cytometry
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Determination of cell survival and proliferation
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Morphological analysis of apoptosis
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Preparation of cell extracts
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Assay for determination of intracellular DAS levels
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Statistical analysis
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Acknowledgements
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References
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