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Research Article
BioDiscovery 20: e11211
https://doi.org/10.3897/biodiscovery.20.e11211 (08 Feb 2017)
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  • Introduction
  • Results
    • Isolation and characterization of cells expressing ABCB1 and ABCG2
    • The effect of ABCB1 and ABCG2 expression on intracellular levels of dasatinib
    • The effect of dasatinib on cell viability and apoptosis induction in cells expressing ABCB1 or ABCG2
  • Discussion
  • Materials and methods
    • Chemicals
    • Cell Culture
    • ABCB1 and ABCG2 expression analysis using flow cytometry
    • Determination of cell survival and proliferation
    • Morphological analysis of apoptosis
    • Preparation of cell extracts
    • Assay for determination of intracellular DAS levels
    • Statistical analysis
  • Acknowledgements
  • References
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