Schematic resume representing the main effects of environmental pollutants in carcinogenesis mediated by the AhR receptor. Exogenous ligands activate AhR and affect several molecular mechanisms resulting in various genes expression that cooperate to promote carcinogenesis.

 

 
  Part of: El Helou M, Cohen P, Diab-Assaf M, Ghayad S (2019) Environmental pollutants-dependent molecular pathways and carcinogenesis. BioDiscovery 22: e29242. https://doi.org/10.3897/biodiscovery.22.e29242