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Review Article
BioDiscovery 5: e8936
https://doi.org/10.7750/BioDiscovery.2012.5.1 (30 Nov 2012)
https://doi.org/10.7750/BioDiscovery.2012.5.1 (30 Nov 2012)
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Abstract
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1. Introduction
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2. Ataxia-telangiectasia mutated (ATM)
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3. Ataxia telangiectasia (A-T) disorder and clinical symptoms
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4. Role of computational modelling in deciphering DDR pathway
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5. Beyond DNA damage repair: ATM’s role in oxidative stress and cellular metabolism
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6. Novel perspectives: Targeting ATM pathway for therapeutic intervention in cancer
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References