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Review Article
BioDiscovery 14: e8962
https://doi.org/10.7750/BioDiscovery.2014.14.2 (23 Dec 2014)
https://doi.org/10.7750/BioDiscovery.2014.14.2 (23 Dec 2014)
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Abstract
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1. The potential of in vitro cell culturing for providing standardised, reliable and safe cardiomyocyte lines for the purposes of research and potential clinical applications
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2. Brief historical overview of the attempts to cultivate rhythmically beating cardiac cells under in vitro conditions
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3. Cardiac development in the human embryo
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4. Sources of stem cells capable of differentiation into cardiomyocytes
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5. Basic types of protocols for induction of targeted differentiation along the mesodermal lineage and direction to cardiogenic fate
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6. Markers for differentiation into cardiomyocyte lineage
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7. Potential advantages of using cultured cardiomyocytes derived by differentiation from pluripotent stem cells lines
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8. Conclusion
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Acknowledgements
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References